8/17/2023 0 Comments Dna sugar phosphate backboneThey are only needed once for the leading strand. Primer, primase, and DNA polymerase III are required to begin the formation of each Okazaki fragment of the lagging strand, and to begin the formation of the continuously produced leading strand. The fragments of the lagging strand are called Okazaki fragments. The lagging strand lags because it's being assembled in reverse and it takes a little more time.įormation of the lagging strand is assembled by fragments being produce moving away from the replication fork in the 5' to 3' direction. In the above image, the leading daughter strand (top) is formed from left to right and the lagging strand is formed from right to left. DNA can only be formed in the 5' to 3' direction because of polymerase III. Then DNA polymerase III allows the addition of free nucleotides in a 5' to 3' direction to produce the growing strand. It is the small portion in red in the above image. In order for this process to work normally, another enzyme called RNA primase (which is a short strand of RNA), precedes DNA polymerase by preparing the molecule in order for it to receive the nucleotides from DNA polymerase. Two phosphate molecules are lost to provide energy for the chemical bonding of the molecules. This molecule contains deoxyribose, a nitrogen base, and three phosphate groups. DNA polymerase reconstructs two daughter strands.Įach nucleotide that is added to the DNA chain is actually a deoxynucleoside triphosphate dNTP molecule. Remember: Helicase splits the parent strand. DNA polymerase is an enzyme that helps put together new DNA strands from the original strand, nucleotide by nucleotide. This occurs at specific regions, called replication origins, that create a replication fork of two polynucleotide strands in antiparallel directions (the middle portion of the diagram). Helicase breaks the hydrogen bonds that link the nitrogen bases and allows the molecule to split. The original strand, shown on the right side of the image, is unzipped or unwound by the enzyme helicase. As a result, this dual-stranded molecule forms a double helix when twisted. Single-rings always pair with double-rings which form complementary base pairs based on the distance between the sugar-phosphate backbones. Adenine and guanine are known as purines (double ring structures) and guanine and thymine are known as pyrimidines (single ring structures). These hydrogen bonds are very weak, which allows for the molecule to be split in replication. Adenine forms a double hydrogen bond with thymine and guanine forms a triple hydrogen bond with cytosine. There are four nitrogen bases in DNA (adenine, thymine, guanine and cytosine). So a strand runs 5' - 3' and the opposing strand runs 3' - 5'. The sugar-phosphate backbones are held together by the nitrogen bases and the backbones run in opposite directions (or are antiparallel). This is the sugar-phosphate backbone of the molecule.Īs the nucleotides link, a sequence of nitrogen bases becomes clear. No matter how many nucleotides are added, there will always be a free 5' carbon with a phosphate group and a 3' carbon with a hydroxyl group. Each nucleotide attaches to another by this method. A covalent bond called a phosphodiester bond links the C5 phosphate group to the C3 hydroxyl group. ![]() The structure of DNA includes an alternating sequence of phosphates and deoxyribose sugars. These orientations must be anti-parallel for DNA's double helix structure to work. The nitrogen base is attached to C1 and the phosphate is attached to C5.Īlso recall that the orientation of the sugars change: the 5' carbon has the oxygen at the "top" and the 3' carbon has the oxygen at the bottom. The carbon immediately to the right of the oxygen atom is #1, and goes around the pentagon structure as shown to the right. It is a 5-carbon sugar with a phosphate and nitrogen base attached. Before we go any further, it is important that you recall the structure of the nucleotide that makes up DNA.
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8/17/2023 0 Comments Julia louis dreyfus age![]() Julia Louis-Dreyfus was inducted into the Television Academy Hall of Fame in 2014. Second-City comedy troupe alum Louis-Dreyfus made her first splash with fans during a 3-year stint on Saturday Night Live, beginning in 1982. She has since hosted the show twice - the first female former SNL cast member to return as host.Ī committed and steadfast defender of the environment, she serves as a member on the leadership council for the Natural Resource Defense Council (NRDC) as well as on the Board of Directors of Heal the Bay and on the Honorary Board of Heal the Ocean. She also played a recurring role in 2003 on Fox's critically acclaimed Arrested Development, among other productions. Her other television credits include numerous appearances on HBO's Curb Your Enthusiasm, which was co-created by Larry David of Seinfeld, and a recurring role on Matt Groening's The Simpsons on FOX. The immensely celebrated actress may also be seen in her prior role as Christine Campbell on CBS comedy The New Adventures of Old Christine. The film was shot in Paris in year 2011 and made. The Northwestern University grad has also received wide acclaim for her starring role as Eva in Fox Searchlight's Enough Said, opposite the late James Gandolfini. In 2011, she appeared in a short HBO film, Picture Paris which was made and directed by her husband, Brad Hall. Louis-Dreyfus has earned worldwide acclaim and recognition for her portrayal of Elaine Benes in the hit NBC series Seinfeld, and Vice President of the United States Selina Meyer in the HBO series Veep. Julia Louis-Dreyfus is an American actress. ![]() It's an easy way to store vocabulary you want to learn.īrowse the web without even noticing that there are foreign languages. Phonetic transcription and transliteration for both original and translation. It works both online and offline, as well as available in dark and light mode. You can save words to Phrasebook directly or shuffle your existing translations to it. Supports French, German, Spanish, Italian, Portuguese, Swedish, and Dutch. Mate will have your back with 103 languages. It lets you easily translate words, texts and speech anywhere on your iPhone or iPad. Mate is an incredibly powerful translator app which is deeply integrated with iOS. Mate has a powerful Mac app and extensions for all major browsers. Mate will translate websites before you even see them. Using Mate Account you can keep translation history and Phrasebook synchronized on all devices. Translate clipboard contents by long-pressing Mate's icon on home screen or from the Search screen. Write messages in your language, Mate will translate them on the fly and send in the recipient's language. Translate in Mail, Notes, PDFs by highlighting text, choosing Share and then Mate from Share Menu. Mate is equally helpful if you're mastering a new language, want to take down a language barrier when going abroad, or just occasionally need to translate a web page, email, message, etc. Solve Language Translator black/white screens issue on Android:įollow the Language Translator android app crash troubleshooting guide Here → Relaunch Language Translator on android.Go back to "Settings" » "Connections" » "Mobile Network" » "Network Mode".Again, got Language Translator » "Mobile Data" » "Allow Background Data Usage".Click Language Translator » "Force Stop".On android, goto "Settings" » "Apps" or "Manage Apps" tab.This issue is usually caused by your network. This Clears both data and cache.įix Language Translator unable to contact server/ Language Translator internet connection errors on Android: On your device, goto "Settings" » click "Apps" » select "Language Translator app" » click "Storage" » click "Clear Data" option.Clear Language Translator App Cache and Data:.Update Language Translator to the latest version on PlayStore.When transforming a part, you also have the ability to select its Mate connector (inferred or existing), or axis. Adjust a parts (and its Mate connector or axis, if desired) location and orientation in 3D space with the option to copy the part in place. On android, goto "Settings" » click Language Translator app. This functionality is available on Onshapes browser, iOS, and Android platforms.Fix Language Translator not working on Android, crashes, errors or is unresponsive:įollow these steps to resolve intermittent Language Translator app issues: 8/17/2023 0 Comments Coherence ending explained![]() ![]() ![]() Katherine hardly fits even into the educational process, although the teacher is trying to “pull her out” In principle, it is not easy for genius people to find their place in society. You may have heard of such a problem as “deviant behavior”, which is most often associated with adolescents who grew up in dysfunctional families and adopted the crime habits of their parents. But few people know that many researchers also refer to the concept of social deviation as children of gifted, talented, genius, since it is as difficult for them to adapt to life among “normal” people as it is for aggressive, embittered and rebellious adolescents. Schizophrenia is often called the “disease of geniuses”, although in fact it is widespread among people with ordinary abilities, it is simply not customary to talk about it. However, it is obvious that a disease affecting higher nervous activity, distorting a person’s thought processes and his picture of the world, and genius, in principle, suggesting a non-standard view of things – concepts that exist in some fairly close planes. The film begins with Katherine talking to the ghost of her recently deceased father, created by her imagination. In the film “Proof” we are shown the life stories of two people at once, whose abilities turned out to be much higher than average: Robert, played by Anthony Hopkins, and his daughter Katherine, whose role went to Gwyneth Paltrow. In general, the theme of genius and accompanying mental disorders has been used very actively in cinema, especially in the last couple of decades: such stories always look intriguing, mysterious, inevitably evoke a wide range of emotions in the audience and, possibly, make them think about something. This question runs through the entire film as a red thread, permeating it through and through. Probably, every person who was born without special talents in any area would sometimes like to be gifted. Probably, every genius, forced to bear the burden of his giftedness throughout his life, without stopping or respite, at least sometimes dreams of becoming “normal”. But in the end, everyone can only be themselves and try to cope with what that means. ![]() In other words, “Proof” is not a legendary movie, although it has everything that could determine such a status. It just came out, perhaps at the wrong time, was filmed by not the most popular director and is devoted to a topic that is not the most acutely social and actively discussed in the press. Oddly enough, the rather interesting, beautiful, well-built “Proof” turned out to be a much less well-known Madden project than, for example, “Shakespeare in Love”, “Reckoning” or even two parts of the “Hotel Marigold” “. The people who still watched this film, for the most part, belong to one of two groups: those who managed to look at the corresponding screening in the cinema in 2005, or fans of Gwyneth Paltrow, Jake Gyllenhaal or Anthony Hopkins, who decided to expand their knowledge about films in which they have ever starred. The psychological drama “Proof” was directed by John Madden based on his own play of the same name. According to the director himself, in principle, he tends to take something from one type of art and transfer it to another, and the presence of such experience, in many ways, helps to create a harmonious and complete picture. ![]() That’s because it’s harder to change your decision when it becomes part of your lifestyle. Although it may be easier in theory to minimize variable costs, it may actually be easier in practice to lower fixed costs. Sometimes creating and sticking to your budget is a matter of a few clever tricks. Regardless, managing fixed and variable expenses can help you reach your financial goals effectively. So, if you are consistently overspending in one area, you may want to cut back or find other ways to reduce spending. Remember, whether you’re setting spending limits, prioritizing expenses, or simply tracking your money, the key to budgeting is to adjust as needed. Staying on top of monthly fees will help you make sure you’re not paying for anything you don’t use. Cancel any monthly services you didn’t realize you were still paying for, too. If your insurance premium is going to go up in the next year, you can plan in advance for that. It could also turn variable expenses into expenses you can anticipate and budget for each month, just like your fixed expenses.Īnother common budgeting tip includes monitoring fixed expenses. This could help you clearly see how much you have left to spend on each category every month. If you want, you could even open separate savings accounts for each variable expense category. You can then set aside that amount each month for each variable expense. Next, see how much you spent on these categories during the previous year and divide that number by 12. For example, you could have a groceries category, a utilities category and a travel expenses category. You can also use the past year’s data to estimate how much you typically spend on categories of variable expenses. But could you stretch a haircut to last six weeks? That would save you roughly three haircuts, which at, say, $40 a pop, is $120. For example, maybe you get a haircut every four weeks. So, if you go through the previous year’s credit and debit card statements, you may begin to see a pattern. Many of your variable expenses may end up being fairly predictable. How to Budget for Variable and Fixed Expenses Cutting back on variable expenses requires more day-to-day willpower than cutting back on fixed expenses. Or maybe you need to decide between buying new clothes or seeing that new movie. You may have to choose between making dinner and getting take-out. Variable expenses may be harder to shrink than fixed expenses because they can affect your lifestyle. For example, you might spend more on electricity in July than you do in December because of air conditioning. Your utility bills may also be variable expenses because they may change from month to month. Grocery shopping is also a variable expense. Buying gas for your car each month is a variable expense, as are car repairs and maintenance. Do you buy conventional or organic produce? Do you get Starbucks or make coffee at home? Not all variable expenses are discretionary expenses, however.Īlthough variable costs are quite often discretionary expenses, some may be necessities. One way of describing variable expenses is that they represent your daily spending decisions. The best part? You only have to make that money-saving decision once to see the reward. However, that $85 per month will turn into $1,020 in one year. The little bit you save on your fixed expenses can add up fast.įor example, if you spend $1,100 instead of $1,185 per month on rent, the quality of your apartment and neighborhood may not change much. This is a great alternative to being frugal with your other spending decisions, such as buying new clothes or ordering takeout. So when you lower your fixed expenses, you lower the percentage of your budget that’s devoted to them. That’s because fixed expenses tend to take up the largest percentage of your budget. When you lower your fixed expenses, you automatically save more money each month or pay period. For example, consider a cheaper gym membership or a different streaming service. Additionally, shop around for alternative car insurance, health insurance, life insurance and homeowners or renters insurance plans to save more money. ![]() If you’re signed up for a monthly service that you rarely use, there may be an alternative plan with a lower price. Some fixed expenses may be discretionary, like a gym membership or streaming service subscription.Īlthough these bills are consistent each month, you may still be able to lower their costs. Typically, these expenses can’t be easily changed. On the plus side, they’re easy to budget for because they generally stay the same and are paid on a regular basis. Typical fixed expenses include car payments, mortgage or rent payments, insurance premiums and real estate taxes. ![]() Nonetheless, if you have a PPTX file on Microsoft SkyDrive, you can import it to edit your presentation. While the app provides the utility to view, create and edit MS Excel spreadsheets and MS Word documents, unfortunately, you cannot create new PowerPoint files from scratch. as is evident from the name of this app, you will require an Office 365 subscription to use this app. Recently, Microsoft has released an iOS app known as Office Mobile for Office 365 subscribers. Installing Microsoft Office 2013 On iOS (iPhone, iPad or iPod Touch) The updates in the Download Center can't be installed on Office Home and Student 2013 RT. Let’s take a look at the various methods by which you can install Microsoft Office 2013 or get official MS Office support on mobile devices. Download Center This update is available for manual download and installation from the Microsoft Download Center. In the wake of this demand, Microsoft has taken steps to provide MS Office support on mobile devices. While Microsoft Office was previously considered to be an application suite only for Windows or mac based computers, its usage on mobile devices is becoming increasingly demanding and people are finding new ways of utilizing Office files on unsupported devices using alternative apps. A few months back we explored the New Features of MS Office 2013 and later also provided you with ways by which you can Download Microsoft Office 2013 Free Trial Version. Windows Business Software Office Suites Microsoft Office Home and Student 2013 Microsoft Office Home and Student 2013 By Microsoft 139.99 Visit Site Premium Upgrade Clicking on the. How do I install my free student download of Microsoft Office You can access your free copy of Microsoft Office (Word, Excel, PowerPoint, Outlook, OneNote and OneDrive) following the below steps: Login to your student email account on the device that you wish to install Microsoft Office on. ![]() Bone-in I find stays juicy where boneless can dry out a bit easier.īeef Consomme – You can find this in the canned soup area of the grocery store. Leave the dish to sit for 5 minutes after removing it from the oven.Pork Chops – You will want to use either a boneless or bone-in pork chop.Make sure the pork chops have reached an internal temperature of at least 145F.Return the dish to the oven and bake the pork chops for an additional 20 minutes until the cheese is completely melted and the fried onions are starting to brown.Sprinkle the crispy fried onions and thyme leaves on top of the cheese.After 25 minutes, remove the dish from the oven and place the slices of provolone cheese on top of the pork chops.Place the baking dish in the oven and bake the pork chops for 25 minutes.Spoon the sour cream mixture on top of the pork chops and spread it out evenly to cover all them all.Whisk all of the ingredients together well. ![]() Add the onion soup mix, gravy mix and thyme leaves to the bowl.Dump the sour cream into a large mixing bowl.Place the pork chops in a single layer in the baking dish.Spray a 9 x 13 inch baking dish well with cooking spray.Ingredients You’ll Need to Make This French Onion Pork Chops: PRINTABLE VERSION OF THE RECIPE CAN BE FOUND AT THE BOTTOM OF THE PAGE If you are looking for a simple and delicious pork chop recipe, then you need to try these French Onion Pork Chops! I served my pork chops with mashed potatoes. Then the cheesy pork chops were ready to serve. I removed the dish from the oven and left it to sit for about five minutes. Then I returned the dish to the oven and continued baking for an additional twenty minutes until the cheese was nicely melted and the fried onions were slightly browned. I sprinkled some thyme leaves over the fried onions. I sprinkled some French’s crispy fried onions on top of the cheese. Then I placed eight slices of provolone cheese on top of the pork chops. Then I placed the baking dish in the oven and baked the pork chops for twenty-five minutes.Īfter twenty-five minutes I removed the dish from the oven. I spread the sour cream mixture out evenly to cover all of the pork chops. Then I spooned the sour cream mixture over the pork chops in the baking dish. I whisked all of the ingredients together well. Then I added some onion soup mix, brown gravy mix and thyme leaves to the bowl. I dumped some sour cream into a large mixing bowl. Then I placed eight boneless pork chops in a single layer in the bottom of the baking dish. To make these pork chops, I started by spraying a 9 x 13 inch baking dish well with cooking spray. Printable Recipe Card with a Full List of Ingredients and Instructions is Located at the Bottom of the Post.īe sure to read through the entire post so that you don’t miss out on any important tips and tricks! This pork chop recipe takes just under an hour from start to finish and produces eight pork chops. These baked pork chops are cooked in a mixture of sour cream, onion soup mix and brown gravy mix. French Onion Pork Chops are an easy baked pork chop recipe loaded with sour cream, onion soup mix, provolone cheese and crispy fried onions.įrench Onion Pork Chops are a delicious dinner recipe the whole family will love. 8/17/2023 0 Comments Sarah dash memorial serviceHe also taught Math Methods to prospective Elementary Education teachers. He was also an Associate Professor at Westminster College, helping countless non-math majors through their final math requirements in order to graduate. At Bryant he coached winning teams in Math Counts competitions, competing in both the state and national levels (1986-1993). He loved teaching middle school students because he felt like that was where he could make the most difference. He taught and mentored many math students in the Salt Lake City School District at Bryant Junior High and West High School. Lewis, Washington, and at Fort Benning, Georgia, he won top honors for perfect physical fitness test scores (that seemed to create quite a stir, but true to form, Dad didn’t give it much thought). He also participated in the ROTC program at the University of Utah. ![]() He continued at the University of Utah, earning a PhD in Education Administration on an NDEA Fellowship (National Defense Education Act) where he wrote his dissertation on “A Conceptual Model of Computer Supported Instructional Systems for Theory and Practice.” This was long before computers were a reality in the classroom, but he could see the influence they would have on education. This UofU record will never be broken because races are measured in meters now and not yards (Dad would say with a twinkle in his eye). In 1968, he and fellow team members took first place in the Western Athletic Conference in the mile relay, which is still an all-time record held for the University of Utah. He was able to complete his undergraduate degree on a track scholarship. This union has brought forth six children (four girls and two boys), twenty grandchildren (nine girls and eleven boys) and eight great grandchildren (six girls and two boys).ĭad graduated from the University of Utah in Teacher Education as a Math major. ![]() He met our mother in the summer of 1964 on a blind date and they have been in love ever since. He was also the recipient of the Hale Award for Outstanding Athlete. He won first place in the state track meet for the 440 yard dash (1962) and the mile relay (1961, 1962). He was athletic, focusing on basketball, football, and track. At Bountiful High he participated in student government and was student body president. They purchased a home in Bountiful, where Larry spent his formative years, going to Stoker Elementary, Bountiful Junior High, and graduating from Bountiful High School in 1962. The family later moved to Centerville when Darrell took a job in Bountiful as a mechanic at a car dealership. He lived in Millard County in central Utah until he was 7 years old, close to the loving influence of his Stott and Whicker grandparents in Fillmore. He was happiest when he was surrounded by his family, making us laugh. ![]() He was brilliant, kind, loving, patient, humble, handsome, funny, athletic, unassuming, righteous, and a disciple of Jesus Christ. He died at home in Herriman, Utah on May 18, 2023, of long term health issues, with his dear wife of nearly 55 years, Susan Eilene Greenwood Stott, by his side.ĭad was the best husband, father, grandfather and great-grandfather and he loved us all so much. Our dear Dad, Larry Whicker Stott was born on Apto Allison Darrell Stott and Portia Olean Whicker in Kamiah, Idaho. 8/17/2023 0 Comments Chromium oxide paste![]() Ken I plan to use my chromium oxide wheel after using the PA-70 leather wheel or the SJ wheel. Strictly out of curiosity, what are the advantages of using chromium oxide instead of PA-70? I will scrape off the excess paste and then see if the results get better after I have honed some more knives. That also explains why I have not gotten the results that I hoped for. I read that the amount of paste I bought should last a life time so I wondered why I had already used half of it. So the problem is that I have applied too much. So do not reapply it too often, only once in 4-6 months.Īhaaa. Quote from: wootz on September 23, 2019, 12:59:02 AMĪfter that, as you start doing your knives, you will see that the edge on the first couple of knives may not come out as sharp as it will on the following knives - the thinner the chromium oxide, the better the result. ![]() If liquid vaseline does it better I would prefer to use that. I think that the Tormek oil does not dilute the chromium oxide very well. To make chromium oxide creamy, you can dilute it with liquid vaseline. I am relieved that you didn't write that I should buy a new wheel. What am I doing wrong? and what must I do now to get a well working chromium oxide wheel and how should I do it in the future? During use it can get a lot worse than shown on the picture and even though I regularly stop and wipe it away, I believe it is not supposed to be like this. The wheel now looks like this (3rd attached picture) and if you look closely you can see that the 'paste' sort of rolls off. I have done this several times prior to using the wheel and now I am unsure if it was the right thing to do. See 2nd attached picture.Īs I had no way of getting it out of the can, I applied a little of the oil that came with the leather wheel and with the help of a toothbrush I was able to dissolve (dilute?) some of the 'paste' and apply it to the wheel. Not like paste at all but more like a block of honing compound. ![]() When I received and opened the can of paste it was to my surprise very hard. I then ordered some chromium oxide paste, which I can no longer find online, but it is shown in the 1st attached picture. I bought a new leather wheel with the purpose of dedicating it to chromium oxide. Basically, it oxidizes as it is cut.I have run into some problems, so I hope you can help me. Following from the numbers in the first paragraph, that occurs in less than 100 nanoseconds. By ~10 L of exposure to oxygen there is a continuous oxide on the surface at 300K. Overall, there is not a huge difference between the two papers. They see chemisorption of oxygen in the first 1-2 L, nucleation and lateral growth of oxide islands up to 10 L, and continued growth of an oxide film above 10 L. Quantity Add to cart Share this: ChrOx is a great way to get a few more shaves out of your straight razors, or polish the bevel after a honing session. Palacio et al., "AES, XPS and EELS study of the initial oxidation of polycrystalline chromium", Surface Science 182(1-2) 41-55 (1987). 8.95 SKU MAG-CHRO-OX We currently have 54 in stock. At normal atmospheric pressure, with 20% oxygen in air, 1 Langmuir of oxygen hits the surface in about 6.6 nanoseconds (yes, nanoseconds).Īnother paper that could be of interest is C. It roughly corresponds to one monolayer equivalent of gas hitting the surface. One Langmuir is the exposure of a surface to a gas pressure of $10^$ Torr for one second. First, a definition of the Langmuir unit, used in the graph in the question, which is not often run across except by vacuum (particularly UHV) folks. |
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